In a large mixing bowl, whisk together the all-purpose flour, sugar, baking powder, baking soda, and salt until well blended.

In another bowl, crack the egg and whisk until lightly beaten. Add the buttermilk, melted butter, and vanilla extract and mix until smooth.

Gently pour the wet ingredients into the dry mixture and stir until just combined; let the batter rest for 5 minutes.

Place a non-stick skillet or griddle on medium heat and warm for about 5 minutes.

Spoon about 1/4 cup of batter onto the skillet for each pancake, cook until bubbles form on the surface, then flip and cook for another 1-2 minutes.

Remove pancakes from skillet, stack on a warm plate, and serve immediately with toppings.